I suggest that a separate section devoted to QA/QC be added to the manuscript.
Special attention should be paid to:
1. description of the validation procedure for the applied/proposed analytical protocol
2. information on metrological characteristics of the analytical procedure, especially Method Quantitation Limit (MQL) values for the entire procedure (from handling of representative samples to statistical and chemometric evaluation of the data sets obtained), and not only for the analytical techniques used during the analysis of the extracts.
I suggest that the protocol described in Journal of Chromatography A (1217, 882-891, 2010) entitled "Estimating uncertainty in analytical procedures based on chromatographic techniques" can be used for evaluation and calculation of expanded uncertainty of results obtained when the procedure described in this manuscript is applied.