主题：【已应助】求助J. Nat. Prod期刊文献一篇 谢谢大家

【作者】：Tsung-Hsien Chou†, Jih-Jung Chen‡, Shiow-Ju Lee§, Michael Y. Chiang#, Cheng-Wei Yang§ and Ih-Sheng Chen*†
【题名】：Cytotoxic Flavonoids from the Leaves of Cryptocarya chinensis
【期刊】：J. Nat. Prod., Article ASAP
【年、卷、期、起止页码】：August 12, 2010
【摘要】：Bioassay-guided fractionation led to the isolation of six new tetrahydroflavanones, cryptochinones A−F (1−6), from the neutral CHCl₃ fraction of Cryptocarya chinensis leaves, together with 14 known compounds (7−20). The structures of these new compounds were determined through spectroscopic analyses, including 2D-NMR, MS, CD, and X-ray crystallographic analysis. Among the isolates, infectocaryone (7) showed cytotoxic activities with IC₅₀ values of 11.0 and 3.7 μM against NCI-H460 and SF-268 cell lines, respectively, and cryptocaryanone A (9) showed cytotoxic activities with IC₅₀ values of 5.1, 4.3, and 5.0 μM against MCF-7, NCI-H460, and SF-268 cell lines, respectively.
【链接】：http://pubs.acs.org/doi/pdfplus/10.1021/np100014j