主题：谁知道那里可以做DSC和PPC？

下面是MicroCal公司的VP-DSC的介绍
Features include:
Fixed-in-place cells for reproducible ultrasensitive performance with low maintenance
Active cell volume ~ 0.5 ml
Cells fabricated from Tantalum 61? which has excellent chemical resistance properties
Operating temperature range of ?0篊 to +130篊
Internal Peltier mechanism ?no external heating or cooling required
User selectable scan rates in the range of 0篊 to 90篊 per hour (upscan)
Unparalleled sensitivity and reproducibility (Figure 3)
User selectable response times for maximum performance
Allow studies of fast or slow transition processes
As little as 12.5 micrograms protein can be used to determine thermodynamic parameters
Self-contained pressurizing system (0-45 psi) for scanning solutions above their boiling point
PPC accessory permits volumetric studies of biopolymers in solution
Solid sample insert kit is available for the study of powders, crystals, and other solid samples
The VP-DSC is an ultrasensitive differential scanning microcalorimeter that uses a cell-feedback network (CFB) to differentially measure heat produced or absorbed between sample and reference cells. Cell design is similar to the VP-ITC (Figure 2).

The VP-DSC was the first calorimeter to feature user-selectable modes of operation: high gain, low gain, and passive. Passive mode is most sensitive and is used to scan broad transitions (e.g. proteins), and the high gain mode is recommended for sharp transitions (e.g. lipids)

请查看美国CSC公司网页：http://www.calscorp.com/Products/6300.htm
相关的应用和技术指标如下
Specifications

The N-DSC is a fixed cell, power-compensation design for the absolute maximum in baseline repeatability. The cells can be pressurized to 6 atmospheres for optimum performance with aqueous solutions over the entire operating temperature range. The baseline repeatability assures that reliable DCp data is obtained from a single scan. The solid-state thermostat provides for scanning in both the heating and cooling directions. The data collection and the powerful DSC data analysis programs run under Microsoft Windows NT™ or Microsoft Windows 2000™ and are compatible with other Windows™ programs.

Heat Measurement: Power Compensation
Rapid Response: Minimum 5 Seconds
Baseline Repeatability: RMS ± 25 nWatts (±0.4 µcal/C) at 1°C/min.
Baseline Noise: ±15 nWatts (±0.2 µcal/min.)
Cell Design: Choice of 0.33 ml Capillary or Cylindrical Cells
Cell Pressurization: 6 Atmospheres Maximum
Temperature Range: -10 to +130°C (Std.) -10 to +160°C (High Temp)

Applications

The N-DSC allows researchers to study almost any thermal transition occuring in dilute biopolymer solution in the temperature range of -10 to +160°C. The ability to measure absolute heat capacities allows the researcher to examine biopolymer solution comformation and solvation as well as subtle changes in folding rather than just complete unfolding. The N-DSC is simply the best instrument available for studies of biopolymer thermal stability and the effects of biopolymer or ligand interactions on macromolecule structure and stability parameters, Tm, DH, and DCp. The built in pressure perturbation capability also offers the researcher the option of studying volumetric properties of biopolymers.

Biopolymer Conformation and Solvation (Absolute Heat Capacities)
Biopolymer Stability (Protein Denaturation)
Biopolymer Structure (Domain Organization)
Ligand Interactions (Drug Binding to Proteins or Nculeic Acids)
Membrane Structure (Lipid Bilayers, Membrane Proteins)
Polynucleotides (Helix to Coil Transitions)
Volumetric Properties of Biopolymers

是说样品在加压的条件下测试呢？
还是说可以耐压的坩锅？
没看太明白：（

加压测定样品，有谁能说的更详细些吗？
想学习一下
谢谢了

原文由 huangmin718 发表:
请查看美国CSC公司网页：http://www.calscorp.com/Products/6300.htm
相关的应用和技术指标如下
Specifications

The N-DSC is a fixed cell, power-compensation design for the absolute maximum in baseline repeatability. The cells can be pressurized to 6 atmospheres for optimum performance with aqueous solutions over the entire operating temperature range. The baseline repeatability assures that reliable DCp data is obtained from a single scan. The solid-state thermostat provides for scanning in both the heating and cooling directions. The data collection and the powerful DSC data analysis programs run under Microsoft Windows NT™ or Microsoft Windows 2000™ and are compatible with other Windows™ programs.

Heat Measurement: Power Compensation
Rapid Response: Minimum 5 Seconds
Baseline Repeatability: RMS ± 25 nWatts (±0.4 µcal/C) at 1°C/min.
Baseline Noise: ±15 nWatts (±0.2 µcal/min.)
Cell Design: Choice of 0.33 ml Capillary or Cylindrical Cells
Cell Pressurization: 6 Atmospheres Maximum
Temperature Range: -10 to +130°C (Std.) -10 to +160°C (High Temp)

Applications

The N-DSC allows researchers to study almost any thermal transition occuring in dilute biopolymer solution in the temperature range of -10 to +160°C. The ability to measure absolute heat capacities allows the researcher to examine biopolymer solution comformation and solvation as well as subtle changes in folding rather than just complete unfolding. The N-DSC is simply the best instrument available for studies of biopolymer thermal stability and the effects of biopolymer or ligand interactions on macromolecule structure and stability parameters, Tm, DH, and DCp. The built in pressure perturbation capability also offers the researcher the option of studying volumetric properties of biopolymers.

Biopolymer Conformation and Solvation (Absolute Heat Capacities)
Biopolymer Stability (Protein Denaturation)
Biopolymer Structure (Domain Organization)
Ligand Interactions (Drug Binding to Proteins or Nculeic Acids)
Membrane Structure (Lipid Bilayers, Membrane Proteins)
Polynucleotides (Helix to Coil Transitions)
Volumetric Properties of Biopolymers