There are 2 ways to know the mass on cantilever. (1) Staic : the deflection of cantilever. (2) Dynamic : the amplitudur or frequecy of cantilever oscillation. To meauseure the mass on cantilever is not easy to do and almost all of AFM makers can not offer standard product. It need special tool to do this. And you need a very soft cantilever. This is a very new technology for bio sensor. You can modify AFm to reach your target. But you must design special monitor system to meet requiremet. For example, laser alignment for multi cantilever, new software for timing analysis.