主题：【分享】欧洲标准化委员会发布致敏性日用香料定量分析方法标准

请问26种致敏性香料都包括哪些香料？

原文由 symmacros(jimzhu) 发表:
请问26种致敏性香料都包括哪些香料？

IFRA的这个上面有写明

Version 3
September 12th, 2007
INTERNATIONAL FRAGRANCE ASSOCIATION
ANALYTICAL PROCEDURE

1. Amyl Cinnamal
CAS: 122-40-7
CAS name: Heptanal, 2-(phenylmethylene)-
Both the (E) and (Z) isomers. .
2. Benzyl Alcohol
CAS: 100-51-6
CAS name: Benzenemethanol
Only one substance is described by this nomenclature.
3. Cinnamyl Alcohol
CAS: 104-54-1
CAS name: 2-Propen-1-ol, 3-phenyl-
Both (E)- and (Z)- isomers are included in our analysis.
4. Citral
CAS: 5392-40-5
CAS name: 2,6-Octadienal, 3,7-dimethyl-
Both (Z)- (Neral: CAS 106-26-3) and (E)- (Geranial: CAS 141-27-5) isomers are
included.
5. Hydroxycitronellal
CAS: 107-75-5
CAS name: Octanal, 7-hydroxy-3,7-dimethyl-
Both (R)- and (S)- enantiomers are included.
International Fragrance Association September 12th, 2007 3/12
6. Eugenol
CAS: 97-53-0
CAS name: Phenol, 2-methoxy-4-(2-propenyl)-
Only one substance described by this nomenclature.
7. Isoeugenol
CAS: 97-54-1
CAS name: Phenol, 2-methoxy-4-(1-propenyl)-
Both (E)- and (Z)- isomers are included.
8. Amylcinnamyl Alcohol
CAS: 101-85-9
CAS name: 1-Heptanol, 2-(phenylmethylene)-
Both the (E) and (Z) isomers.
9. Benzyl Salicylate
CAS: 118-58-1
CAS name: Benzoic acid, 2-hydroxy-, phenylmethyl ester
Only one substance described by this nomenclature.
10. Cinnamal
CAS: 104-55-2
CAS name: 2-Propenal, 3-phenyl-
Both (E)- (trans- CAS 14371-10-9) and (Z)- (cis- CAS 57194-69-1) isomers are
included.
11. Coumarin
CAS: 91-64-5
CAS name: 2H-1-Benzopyran-2-one
Only one substance described by this nomenclature.
12. Geraniol
CAS: 106-24-1
CAS name: 2,6-Octadien-1-ol, 3,7-dimethyl-, (E)-
Only one substance described by this nomenclature. The (Z)- isomer (Nerol: CAS
106-25-2) is not included.
International Fragrance Association September 12th, 2007 4/12
13. Hydroxyisohexyl- 3-cyclohexene carboxaldehyde
Trade name : Lyral
CAS: 31906-04-4
CAS name: 3-Cyclohexene-1-carboxaldehyde, 4-(4-hydroxy-4-methylpentyl)-
Only this isomer is included in our analysis although some commercial qualities of this
substance usually contain lesser quantities of the 3-Cyclohexene-1-
carboxaldehyde, 3-(4-hydroxy-4-methylpentyl)- isomer.
14. Anise Alcohol
CAS: 105-13-5
CAS name: Benzenemethanol, 4-methoxy-
Only one substance described by this nomenclature.
15. Benzyl Cinnamate
CAS: 103-41-3
CAS name: 2-Propenoic acid, 3-phenyl-, phenylmethyl ester
Both (E)- and (Z)- cinnamate isomers are included.
16. Farnesol
CAS: 4602-84-0
CAS name: 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-
Undefined mixture of four isomers (predominantly the (E,E) ("trans, trans-Farnesol": CAS
106-28-5) and (Z,E) ("trans, cis-Farnesol": CAS 3790-71-4) .
17. Butylphenyl Methylpropional
Trade name: Lilial
CAS: 80-54-6
CAS name: Benzenepropanal, 4-(1,1-dimethylethyl)-.alpha.-methyl-
Both (R)- and (S)- enantiomers are included in our analysis. The isomeric 2-(3-tert-
Butylbenzyl) propionaldehyde is not included.
18. Linalool
CAS: 78-70-6
CAS name: 1,6-Octadien-3-ol, 3,7-dimethyl-
Both (R)- (CAS # 126-91-0) and (S)- (CAS # 126-90-9) enantiomers are included.
19. Benzyl Benzoate
CAS: 120-51-4
CAS name: Benzoic acid, phenylmethyl ester
Only one substance described by this nomenclature.
International Fragrance Association September 12th, 2007 5/12
20. Citronellol
CAS: 106-22-9
CAS name: 6-Octen-1-ol, 3,7-dimethyl-
Both (R)- ((-): CAS 1117-61-9 )and (S)- ((+): CAS 7540-51-4) enantiomers are
included.
21. Hexyl Cinnamal
CAS: 101-86-0
CAS name: Octanal, 2-(phenylmethylene)-
Both the (E) and (Z) isomers. .
22. Limonene
CAS: 5989-27-5
CAS name: Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (R)-
Both (R)- and (S)- (CAS # 5989- 54-8) enantiomers may have to be taken into
account . (See special note on LIMONENE).
23. Methyl 2-Octynoate
CAS: 111-12-6
CAS name: 2-Octynoic acid, methyl ester
Only one substance described by this nomenclature.
24. Alpha-Isomethyl Ionone
CAS: 127-51-5
CAS name: 3-Buten-2-one, 3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-
Both (E)- and (Z)- isomers of the specified structural isomer are included in the analysis.
Even though other structural isomers are often present in commercial quantities of this
substance, they are not included.

另外两个是Tree moss extract和Oak moss extract

原文由 symmacros(jimzhu) 发表:
欧洲的相关法规和指令[1]规定，当26种致敏性香料[2]的用量超过指定量时，化妆品、洗涤剂和家用产品等应在标签上对这些香料进行标注。IFRA推荐使用该标准，但是由于版权问题，不能够提供标准文本。

法规和指令具体是哪个呢？是不是DIRECTIVE 2003/15/EC这个呀？谢谢！

原文由 symmacros(jimzhu) 发表:
根据国际日用香料协会（IFRA）的信息通讯（IL 947），今年九月初，欧洲标准化委员会发布了关于“致敏剂分析方法——消费品中致敏性香料的定量分析—气相色谱法”（CEN Standard 16274:2012）的新标准。该标准是在IFRA的草案基础上制定的，日用香料行业组织和资助了此项标准的制定工作。欧洲的相关法规和指令[1]规定，当26种致敏性香料[2]的用量超过指定量时，化妆品、洗涤剂和家用产品等应在标签上对这些香料进行标注。IFRA推荐使用该标准，但是由于版权问题，不能够提供标准文本。

标准采用气相色谱—质谱联机（GC-MS），利用两个极性不同的色谱柱结合特定定量和数据处理方法进行分析，该方法适用于对化妆品原料或产品中24种日用香料的分离和定量分析。由于橡苔提取物和树苔提取物属于天然复合物，成分组成复杂，很难通过现有的方法进行定量分析，因此标准未涵盖这两个日用香料。

最迟到2013年3月，此标准应被转化为（欧洲各国的）国家标准，不符合此标准规定的国家标准应同时废止。实施这一标准的国家包括：奥地利、比利时、保加利亚、克罗地亚、塞浦路斯、捷克、丹麦、爱沙尼亚、芬兰、马其顿、法国、德国、希腊、匈牙利、冰岛、爱尔兰、意大利、拉脱维亚、立陶宛、卢森堡、马耳他、荷兰、挪威、波兰、葡萄牙、罗马尼亚、斯洛伐克、斯洛文尼亚、西班牙、瑞典、瑞士、土耳其和英国。

有没有这个资料可以分享啊？CEN Standard 16274:2012

原文由 wuzidun(wuzidun) 发表:

原文由 symmacros(jimzhu) 发表:
请问26种致敏性香料都包括哪些香料？

IFRA的这个上面有写明

Version 3
September 12th, 2007
INTERNATIONAL FRAGRANCE ASSOCIATION
ANALYTICAL PROCEDURE

1. Amyl Cinnamal
CAS: 122-40-7
CAS name: Heptanal, 2-(phenylmethylene)-
Both the (E) and (Z) isomers. .
2. Benzyl Alcohol
CAS: 100-51-6
CAS name: Benzenemethanol
Only one substance is described by this nomenclature.
3. Cinnamyl Alcohol
CAS: 104-54-1
CAS name: 2-Propen-1-ol, 3-phenyl-
Both (E)- and (Z)- isomers are included in our analysis.
4. Citral
CAS: 5392-40-5
CAS name: 2,6-Octadienal, 3,7-dimethyl-
Both (Z)- (Neral: CAS 106-26-3) and (E)- (Geranial: CAS 141-27-5) isomers are
included.
5. Hydroxycitronellal
CAS: 107-75-5
CAS name: Octanal, 7-hydroxy-3,7-dimethyl-
Both (R)- and (S)- enantiomers are included.
International Fragrance Association September 12th, 2007 3/12
6. Eugenol
CAS: 97-53-0
CAS name: Phenol, 2-methoxy-4-(2-propenyl)-
Only one substance described by this nomenclature.
7. Isoeugenol
CAS: 97-54-1
CAS name: Phenol, 2-methoxy-4-(1-propenyl)-
Both (E)- and (Z)- isomers are included.
8. Amylcinnamyl Alcohol
CAS: 101-85-9
CAS name: 1-Heptanol, 2-(phenylmethylene)-
Both the (E) and (Z) isomers.
9. Benzyl Salicylate
CAS: 118-58-1
CAS name: Benzoic acid, 2-hydroxy-, phenylmethyl ester
Only one substance described by this nomenclature.
10. Cinnamal
CAS: 104-55-2
CAS name: 2-Propenal, 3-phenyl-
Both (E)- (trans- CAS 14371-10-9) and (Z)- (cis- CAS 57194-69-1) isomers are
included.
11. Coumarin
CAS: 91-64-5
CAS name: 2H-1-Benzopyran-2-one
Only one substance described by this nomenclature.
12. Geraniol
CAS: 106-24-1
CAS name: 2,6-Octadien-1-ol, 3,7-dimethyl-, (E)-
Only one substance described by this nomenclature. The (Z)- isomer (Nerol: CAS
106-25-2) is not included.
International Fragrance Association September 12th, 2007 4/12
13. Hydroxyisohexyl- 3-cyclohexene carboxaldehyde
Trade name : Lyral
CAS: 31906-04-4
CAS name: 3-Cyclohexene-1-carboxaldehyde, 4-(4-hydroxy-4-methylpentyl)-
Only this isomer is included in our analysis although some commercial qualities of this
substance usually contain lesser quantities of the 3-Cyclohexene-1-
carboxaldehyde, 3-(4-hydroxy-4-methylpentyl)- isomer.
14. Anise Alcohol
CAS: 105-13-5
CAS name: Benzenemethanol, 4-methoxy-
Only one substance described by this nomenclature.
15. Benzyl Cinnamate
CAS: 103-41-3
CAS name: 2-Propenoic acid, 3-phenyl-, phenylmethyl ester
Both (E)- and (Z)- cinnamate isomers are included.
16. Farnesol
CAS: 4602-84-0
CAS name: 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-
Undefined mixture of four isomers (predominantly the (E,E) ("trans, trans-Farnesol": CAS
106-28-5) and (Z,E) ("trans, cis-Farnesol": CAS 3790-71-4) .
17. Butylphenyl Methylpropional
Trade name: Lilial
CAS: 80-54-6
CAS name: Benzenepropanal, 4-(1,1-dimethylethyl)-.alpha.-methyl-
Both (R)- and (S)- enantiomers are included in our analysis. The isomeric 2-(3-tert-
Butylbenzyl) propionaldehyde is not included.
18. Linalool
CAS: 78-70-6
CAS name: 1,6-Octadien-3-ol, 3,7-dimethyl-
Both (R)- (CAS # 126-91-0) and (S)- (CAS # 126-90-9) enantiomers are included.
19. Benzyl Benzoate
CAS: 120-51-4
CAS name: Benzoic acid, phenylmethyl ester
Only one substance described by this nomenclature.
International Fragrance Association September 12th, 2007 5/12
20. Citronellol
CAS: 106-22-9
CAS name: 6-Octen-1-ol, 3,7-dimethyl-
Both (R)- ((-): CAS 1117-61-9 )and (S)- ((+): CAS 7540-51-4) enantiomers are
included.
21. Hexyl Cinnamal
CAS: 101-86-0
CAS name: Octanal, 2-(phenylmethylene)-
Both the (E) and (Z) isomers. .
22. Limonene
CAS: 5989-27-5
CAS name: Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (R)-
Both (R)- and (S)- (CAS # 5989- 54-8) enantiomers may have to be taken into
account . (See special note on LIMONENE).
23. Methyl 2-Octynoate
CAS: 111-12-6
CAS name: 2-Octynoic acid, methyl ester
Only one substance described by this nomenclature.
24. Alpha-Isomethyl Ionone
CAS: 127-51-5
CAS name: 3-Buten-2-one, 3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-
Both (E)- and (Z)- isomers of the specified structural isomer are included in the analysis.
Even though other structural isomers are often present in commercial quantities of this
substance, they are not included.

另外两个是Tree moss extract和Oak moss extract

这些都还是日化香精常用的原料之一。

能下载下该标准吗？