主题：【资料】质谱在药物化学中的应用（原版电子书）

书名：Mass Spectrometry in Medicinal Chemistry
作者：Klaus T. Wanner and Georg Hofner
出版社：WILEY-VCH Verlag GmbH
时间：2007
目录：1 Mass Spectrometry in Bioanalysis – Methods, Principles and
Instrumentation
2 Drug Screening Using Gel Permeation Chromatography Spin Columns
Coupled with ESI-MS
3 ALIS: An Affinity Selection–Mass Spectrometry System for the Discovery and Characterization of Protein–Ligand Interactions
4 Library Screening Using Ultrafiltration and Mass Spectrometry
5 Continuous-flow Systems for Ligand Binding and Enzyme Inhibition Assays Based on Mass Spectrometry
6 Frontal Affinity Chromatography – Mass Spectrometry for Ligand Discovery and Characterization
7 MS Binding Assays – An Alternative to Radioligand Binding
8 Laser Desorption Assays – MALDI-MS, DIOS-MS, and SAMDI-MS
9 Tethering: Fragment-based Drug Discovery by Mass Spectrometry
10 Interrogation of Noncovalent Complexes by ESI-MS: A Powerful Platform for High Throughput Drug Discovery
11 Quantification of Protein–Ligand Interactions in Solution by Hydrogen/Deuterium Exchange (PLIMSTEX)
12 Protein-targeting Drug Discovery Guided by Hydrogen/Deuterium Exchange Mass Spectrometry (DXMS)
13 Mass Spectrometry in Early Pharmacokinetic Investigations
Mass Spectrometry in Medicinal Chemistry