主题:【讨论】-研究发现“避蚊胺” 对神经系统有害

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luyongxian
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研究发现“避蚊胺” 对神经系统有害
英国《BMC生物学》杂志5日刊登一项最新研究结果表明,驱蚊剂“避蚊胺”(DEET)对中枢神经系统中一种关键酶的活性有抑制作用,研究人员认为有必要重新深入研究这种驱蚊剂的安全性。
    由法国研究人员领导的一个国际小组研究发现,“避蚊胺”能抑制乙酰胆碱酯酶的活性,而这种酶在昆虫和哺乳动物的中枢神经系统中都非常关键。
    研究人员说,“避蚊胺”常与其他杀虫剂混用,但它在与氨基甲酸盐类杀虫剂混用时毒性会增强。研究人员认为,出于对公众健康安全的考虑,应该重新对“避蚊胺”的安全性进行深入研究。
    “避蚊胺”于20世纪中期被发明,化学名称为二乙基甲苯酰胺。它可以有效趋避蚊、蠓、蚋、蝇和跳蚤等昆虫,因此在全世界一直得到广泛使用。(信息来源:新华网)
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我在故我思
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Effects on health
As a precaution, manufacturers advise that DEET products should not be used under clothing or on damaged skin, and that preparations be washed off after they are no longer needed or between applications.[11] DEET can act as an irritant;[4] in rare cases, it may cause skin reactions.[11]

In the DEET Reregistration Eligibility Decision (RED), the United States Environmental Protection Agency‎ (EPA) reported 14 to 46 cases of potential DEET-associated seizures, including 4 deaths. The EPA states: "... it does appear that some cases are likely related to DEET toxicity," but observed that with 30% of the US population using DEET, the likely seizure rate is only about one per 100 million users.[12]

The Pesticide Information Project of Cooperative Extension Offices of Cornell University states that "Everglades National Park employees having extensive DEET exposure were more likely to have insomnia, mood disturbances and impaired cognitive function than were lesser exposed co-workers". [13]

When used as directed, products containing between 10% to 30% DEET have been found by The American Academy of Pediatrics to be safe to use on children as well as adults but recommends that DEET not be used on infants less than two months old.[11]

Recently, DEET has been found to inhibit the activity of a central nervous system enzyme, acetylcholinesterase, in both insects and mammals.[14] This enzyme is involved in the hydrolysis of the neurotransmitter acetylcholine, thus playing a role in the function of the neurons which control muscles. Because of this property, many insecticides are used to block acetylcholinesterase, which leads to an excessive accumulation of acetylcholine at the synaptic cleft, causing neuromuscular paralysis and death by asphyxiation.[15] DEET is commonly used in combination with insecticides and has the capacity to strengthen the toxicity of carbamates, a class of insecticides known to block acetylcholinesterase. These findings bring evidence that, besides having known toxic effects on the olfactory system, DEET also acts on the brain of both insects and mammals, and that its toxicity is strengthened in combination with other insecticides.
这是在维基百科中检索到的
雾非雾
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看商场里卖的蚊香片上,主要都是菊酯类杀虫剂(烯丙菊酯、丙炔菊酯等)。应该也好不哪去,没办法。
zhang3006
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快乐
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最好不要弄成六六六、滴滴涕这样的农药,刚开始时,效果很好,但最终还是被禁止了
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