原文由 lucia_J(hgy154) 发表:原文由 yuduoling(yuduoling) 发表:原文由 无机麦地(shuiyang88) 发表:
How can mass spectrometry help biochemists?
有时候可能外行人会问下,这个仪器能干什么呢?这样的问题该如何回答
如果有人问这个仪器能干什么?就回答他说这个仪器可以分析
那如果人家问都可以分析啥呀?可以测三聚氰胺么?
上次一客户看到我的GCMS就这样问滴。
原文由 无机麦地(shuiyang88) 发表:
看到这几点比较全面
Accurate molecular weight measurements:
sample confirmation, to determine the purity of a sample, to verify amino acid substitutions, to detect post-translational modifications, to calculate the number of disulphide bridges
Reaction monitoring:
to monitor enzyme reactions, chemical modification, protein digestion
Amino acid sequencing:
sequence confirmation, de novo characterisation of peptides, identification of proteins by database searching with a sequence "tag" from a proteolytic fragment
Oligonucleotide sequencing:
the characterisation or quality control of oligonucleotides
Protein structure:
protein folding monitored by H/D exchange, protein-ligand complex formation under physiological conditions, macromolecular structure determination