Streptomyces hygroscopicus RAPA, Rapamune, Sirolimus, RPM, Antibiotic AY 22989 Rapamycin (Sirolimus) is a macrolide compound that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus (Rapamycin) is a potent immunosuppressant. Sirolimus (Rapamycin) possesses both antifungal and antineoplastic properties. 53123-88-9 12, 8288 914.2
C51H79NO13
Specifications Appearance: Off-white to slight yellow powder Purity At least 97% by TLC, HPLC max: 265, 277, 287 Melting point 178°C-182°C Solubility Rapamycin (Sirolimus) gives clear colorless solution at 50mg/ml DMSO Storage -20°C. Protect from light and moisture. Hygroscopic.
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