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Experimental design for S180 tumor-bearingmice
The Kunming mice were randomly divided intofive groups (n=8/group): the control group and the four experimental group. In theexperimental groups, the mice were orally administered BFO-1 (250, 500, and1000 mg/ kg) every day for a week and the control group was administered theequivalent volume of saline. The five groups of mice were subcutaneously inoculatedwith 0.2 ml of S180 cell suspension (1×107 ml)in the right upper limb on day 8, and then BFO-1 and saline were administeredon the other 9 days. The mice were sacrificed, and the tumor tissue wasdetached and weighed. The tumor inhibition rate was calculated according to thefollowing formula:Tumor inhibition rate (%) = (Wcontrol - Wtreated)/Wcontrol×100%, where Wtreated and Wcontrol were theaverage tumor weights of the treated and control groups, respectively. The phagocyticactivity of the peritoneal macrophages and the production of NO were measuredas described above.
这是我看的文献中的一部分,我想问问实验组有四组,给予样品处理的只有3组,对照组是用等量的生理盐水处理,请问还有一组实验组的处理是怎样的?我看这篇文献的结果图中是model组、250、500、1000剂量组,请问这个model组是怎么来的?
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