[摘要] 生物质谱因其高灵敏度、高准确度、快速、易于自动化等特点,在生命科学 领域的应用和研究日益广泛。本文就其近年来在蛋白质、核酸、糖类、药物代谢以及微 生物检验等方面的应用及进展作一综述。 [关键词] 生物质谱;电喷雾;基质辅助激光解吸附;串联质谱 [中国图书资料分类法分类号] O657.6 [文献标示码] A [文章编号] Applications and progress on bio-mass spectrometry YING WAN TAO,QIAN XIAO HONG National Center of Biomedical Analysis, Academy of Military Medical Scie nces, Beijing 100850 [Abstract] For its high sensitivity, accuracy, high speed and easy to au tomate, bio-mass spectrometry develops very fast . This article reviews its applications and latest progress in the field of proteins/peptides, nucleoti des, carbohydrates, pharmaceutical metabolism and microbiology in the past y ears. [Key words] bio-mass spectrometry; electrospray ionization; matrix-assis ted laser desorption ionization; tandem mass spectrometry
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