主题：【讨论】有谁用USP<197M>红外测试方法测试过样品的？

原文由 tangtang(tangtang) 发表:

原文由 影子(hyheying) 发表:

原文由 tangtang(tangtang) 发表:

原文由 影子(hyheying) 发表:

原文由 天津天光光学仪器(SH101430) 发表:
应该根据样品的特性来选择分析方法吧。

有的品种在药典专论中已明确写了用197M方法的

有没有对照图谱？做一下看看。

因为没有矿物油，没试过，USP一般没有对照图谱，通常是与对照品图谱比较

配套红外实验用品的厂家都有卖的，可以买一瓶备用。或者直接找红外厂家，肯定可以买到。

好像英国药典、日本药典是有标准图谱的？

有一部分有，比较少

原文由 tangtang(tangtang) 发表:
《药品红外光谱集》第四卷中提到有：

1.压片法

2.糊法

3.膜法

4.溶液法

5.衰减全反射法

6.气体法

美国药典也是六种方法，有对应关系吗？

Six methods are indicated for the preparation of previously dried test specimens and Reference Standards for analysis. The reference <197K> in a monograph signifies that the substance under examination is mixed intimately with potassium bromide. The reference <197M> in a monograph signifies that the substance under examination is finely ground and dispersed in mineral oil. The reference <197F> in a monograph signifies that the substance under examination is suspended neat between suitable (for example, sodium chloride or potassium bromide) plates. The reference <197S> signifies that a solution of designated concentration is prepared in the solvent specified in the individual monograph, and the solution is examined in 0.1-mm cells unless a different cell path length is specified in the individual monograph. The reference <197A> signifies that the substance under examination is intimately in contact with an internal reflection element for attenuated total reflectance (ATR) analysis. The reference <197E> signifies that the substance under examination is pressed as a thin sample against a suitable plate for IR microscopic analysis.

原文由 影子(hyheying) 发表:

原文由 tangtang(tangtang) 发表:

原文由 影子(hyheying) 发表:

原文由 tangtang(tangtang) 发表:

原文由 影子(hyheying) 发表:

原文由 天津天光光学仪器(SH101430) 发表:
应该根据样品的特性来选择分析方法吧。

有的品种在药典专论中已明确写了用197M方法的

有没有对照图谱？做一下看看。

因为没有矿物油，没试过，USP一般没有对照图谱，通常是与对照品图谱比较

配套红外实验用品的厂家都有卖的，可以买一瓶备用。或者直接找红外厂家，肯定可以买到。

好像英国药典、日本药典是有标准图谱的？

有一部分有，比较少

好像有欧洲药典标准图谱卖的，一张就要两千多，品种也不多。

原文由 影子(hyheying) 发表:

原文由 tangtang(tangtang) 发表:
《药品红外光谱集》第四卷中提到有：

1.压片法

2.糊法

3.膜法

4.溶液法

5.衰减全反射法

6.气体法

美国药典也是六种方法，有对应关系吗？

Six methods are indicated for the preparation of previously dried test specimens and Reference Standards for analysis. The reference <197K> in a monograph signifies that the substance under examination is mixed intimately with potassium bromide. The reference <197M> in a monograph signifies that the substance under examination is finely ground and dispersed in mineral oil. The reference <197F> in a monograph signifies that the substance under examination is suspended neat between suitable (for example, sodium chloride or potassium bromide) plates. The reference <197S> signifies that a solution of designated concentration is prepared in the solvent specified in the individual monograph, and the solution is examined in 0.1-mm cells unless a different cell path length is specified in the individual monograph. The reference <197A> signifies that the substance under examination is intimately in contact with an internal reflection element for attenuated total reflectance (ATR) analysis. The reference <197E> signifies that the substance under examination is pressed as a thin sample against a suitable plate for IR microscopic analysis.

大串英文看不懂啊，microscopic是不是显微的意思？

可以用液体池做吗？

原文由 鸟儿—飞翔(xiaolingzi1027) 发表:

可以用液体池做吗？

用液体池应该是不错的方法。

原文由 tangtang(tangtang) 发表:

原文由 影子(hyheying) 发表:

原文由 tangtang(tangtang) 发表:
《药品红外光谱集》第四卷中提到有：

1.压片法

2.糊法

3.膜法

4.溶液法

5.衰减全反射法

6.气体法

美国药典也是六种方法，有对应关系吗？

Six methods are indicated for the preparation of previously dried test specimens and Reference Standards for analysis. The reference <197K> in a monograph signifies that the substance under examination is mixed intimately with potassium bromide. The reference <197M> in a monograph signifies that the substance under examination is finely ground and dispersed in mineral oil. The reference <197F> in a monograph signifies that the substance under examination is suspended neat between suitable (for example, sodium chloride or potassium bromide) plates. The reference <197S> signifies that a solution of designated concentration is prepared in the solvent specified in the individual monograph, and the solution is examined in 0.1-mm cells unless a different cell path length is specified in the individual monograph. The reference <197A> signifies that the substance under examination is intimately in contact with an internal reflection element for attenuated total reflectance (ATR) analysis. The reference <197E> signifies that the substance under examination is pressed as a thin sample against a suitable plate for IR microscopic analysis.

大串英文看不懂啊，microscopic是不是显微的意思？

好象是这意思，只是没用过，不太懂

原文由 tangtang(tangtang) 发表:

原文由 鸟儿—飞翔(xiaolingzi1027) 发表:

可以用液体池做吗？

用液体池应该是不错的方法。

因为我只有液体池，做的都是油样。

原文由 影子(hyheying) 发表:

原文由 tangtang(tangtang) 发表:

原文由 影子(hyheying) 发表:

原文由 tangtang(tangtang) 发表:
《药品红外光谱集》第四卷中提到有：

1.压片法

2.糊法

3.膜法

4.溶液法

5.衰减全反射法

6.气体法

美国药典也是六种方法，有对应关系吗？

Six methods are indicated for the preparation of previously dried test specimens and Reference Standards for analysis. The reference <197K> in a monograph signifies that the substance under examination is mixed intimately with potassium bromide. The reference <197M> in a monograph signifies that the substance under examination is finely ground and dispersed in mineral oil. The reference <197F> in a monograph signifies that the substance under examination is suspended neat between suitable (for example, sodium chloride or potassium bromide) plates. The reference <197S> signifies that a solution of designated concentration is prepared in the solvent specified in the individual monograph, and the solution is examined in 0.1-mm cells unless a different cell path length is specified in the individual monograph. The reference <197A> signifies that the substance under examination is intimately in contact with an internal reflection element for attenuated total reflectance (ATR) analysis. The reference <197E> signifies that the substance under examination is pressed as a thin sample against a suitable plate for IR microscopic analysis.

大串英文看不懂啊，microscopic是不是显微的意思？

好象是这意思，只是没用过，不太懂

中国药典药品检验用红外显微镜的好像不多。多层包装材料红外鉴别就要用红外显微镜。

原文由 鸟儿—飞翔(xiaolingzi1027) 发表:

原文由 tangtang(tangtang) 发表:

原文由 鸟儿—飞翔(xiaolingzi1027) 发表:

可以用液体池做吗？

用液体池应该是不错的方法。

因为我只有液体池，做的都是油样。

品种比较单一？