主题：【求助】添加剂毒性有这么一句话，啥意思

添加剂在使用前必须进行毒理学实验，其毒性级别进行测试，所以有毒性之说。无毒也是其中的毒性级别之一。

GRAS是一般认为安全。

不仅仅是添加剂，很多东西都有毒理学的实验，他是门科学，不代表有毒，只是对人体危害性等级的一种划分

GRAS：FDA-21CRF182.1073
这个是不是  GRAS：FDA-21CFR 182.1073 ？
下面内容选自：FDA-21CFR 182.1073

182.1073 Phosphoric acid.
(a) Product. Phosphoric acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing practice.

译文：
磷酸
（一）品名：磷酸
（二）使用条件：依据良好生产操作规范使用时，此物质通常被认为是安全的。

相关解释：
GRAS：是美国FDA评价食品添加剂的安全性指标。“通常被认为是安全的“ Generally Recognized as Safe.”
CFR：Code of Federal Regulations(美国联邦管理法规)
确保食品添加剂的绝对安全使用，世界各国对各种食品添加剂能否使用、适用范围和最大使用量，都有严格的规定，要受法规法律的制约。在国际上被公认的食品添加剂安全性指标有LD50，GRAS 和ADI。
LD50（大鼠，经口）是判断食品添加剂安全性的常用指标，也是任何食品添加剂都必须进行的毒理学评价中的第一个阶段急性毒性试验指标，LD50越大表明其毒性越小，在食品使用时其安全性越高。
GRAS是美国 FDA评价食品添加剂的安全性指标。根据FDA的规定，苯甲酸被列为一般公认的安全类食品添加剂（GPAS）。
ADI（Acceptable　Daily Intake）值为每日人体每千克体重允许摄入的毫克数，数值是由FAO/WHO（1994）规定的。只要按照国标规定的添加量使用是不会有安全问题的

FDA-21CFR 182.1073 这应该是个法规指令吧

这个您能看懂的，我就不管翻译了！

Code of Federal Regulations - Title 21 - Food and Drugs

The Code of Federal Regulations (CFR) is a codification of the general and permanent rules published in the Federal Register by the Executive departments and agencies of the Federal Government. Title 21 of the CFR is reserved for rules of the Food and Drug Administration. Each title (or volume) of the CFR is revised once each calendar year. A revised Title 21 is issued on approximately April 1st of each year and is usually available here several months later.

TITLE 21--FOOD AND DRUGS
CHAPTER I--FOOD AND DRUG ADMINISTRATION
DEPARTMENT OF HEALTH AND HUMAN SERVICES
SUBCHAPTER B--FOOD FOR HUMAN CONSUMPTION (CONTINUED)  PART 182 SUBSTANCES GENERALLY RECOGNIZED AS SAFE
   

Subpart A--General Provisions
  § 182.1 - Substances that are generally recognized as safe.
  § 182.10 - Spices and other natural seasonings and flavorings.
  § 182.20 - Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
  § 182.40 - Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings.
  § 182.50 - Certain other spices, seasonings, essential oils, oleoresins, and natural extracts.
  § 182.60 - Synthetic flavoring substances and adjuvants.
  § 182.70 - Substances migrating from cotton and cotton fabrics used in dry food packaging.
  § 182.90 - Substances migrating to food from paper and paperboard products.
  § 182.99 - Adjuvants for pesticide chemicals.

Subpart B--Multiple Purpose GRAS Food Substances
  § 182.1045 - Glutamic acid.
  § 182.1047 - Glutamic acid hydrochloride.
  § 182.1057 - Hydrochloric acid.
  § 182.1073 - Phosphoric acid.
  § 182.1087 - Sodium acid pyrophosphate.
  § 182.1125 - Aluminum sulfate.
  § 182.1127 - Aluminum ammonium sulfate.
  § 182.1129 - Aluminum potassium sulfate.
  § 182.1131 - Aluminum sodium sulfate.
  § 182.1180 - Caffeine.
  § 182.1217 - Calcium phosphate.
  § 182.1235 - Caramel.
  § 182.1320 - Glycerin.
  § 182.1480 - Methylcellulose.
  § 182.1500 - Monoammonium glutamate.
  § 182.1516 - Monopotassium glutamate.
  § 182.1711 - Silica aerogel.
  § 182.1745 - Sodium carboxymethylcellulose.
  § 182.1748 - Sodium caseinate.
  § 182.1778 - Sodium phosphate.
  § 182.1781 - Sodium aluminum phosphate.
  § 182.1810 - Sodium tripolyphosphate.

Subpart C--Anticaking Agents
  § 182.2437 - Magnesium silicate.
  § 182.2727 - Sodium aluminosilicate.
  § 182.2729 - Sodium calcium aluminosilicate, hydrated.
  § 182.2906 - Tricalcium silicate.
  § 182.2122 - Aluminum calcium silicate.
  § 182.2227 - Calcium silicate.

Subpart D--Chemical Preservatives
  § 182.3013 - Ascorbic acid.
  § 182.3041 - Erythorbic acid.
  § 182.3089 - Sorbic acid.
  § 182.3109 - Thiodipropionic acid.
  § 182.3149 - Ascorbyl palmitate.
  § 182.3169 - Butylated hydroxyanisole.
  § 182.3173 - Butylated hydroxytoluene.
  § 182.3189 - Calcium ascorbate.
  § 182.3225 - Calcium sorbate.
  § 182.3280 - Dilauryl thiodipropionate.
  § 182.3616 - Potassium bisulfite.
  § 182.3637 - Potassium metabisulfite.
  § 182.3640 - Potassium sorbate.
  § 182.3731 - Sodium ascorbate.
  § 182.3739 - Sodium bisulfite.
  § 182.3766 - Sodium metabisulfite.
  § 182.3795 - Sodium sorbate.
  § 182.3798 - Sodium sulfite.
  § 182.3862 - Sulfur dioxide.
  § 182.3890 - Tocopherols.

Subpart E--Emulsifying Agents [Reserved]

Subpart F--Dietary Supplements [Reserved]

Subpart G--Sequestrants1
  § 182.6085 - Sodium acid phosphate.
  § 182.6197 - Calcium diacetate.
  § 182.6203 - Calcium hexametaphosphate.
  § 182.6215 - Monobasic calcium phosphate.
  § 182.6285 - Dipotassium phosphate.
  § 182.6290 - Disodium phosphate.
  § 182.6757 - Sodium gluconate.
  § 182.6760 - Sodium hexametaphosphate.
  § 182.6769 - Sodium metaphosphate.
  § 182.6778 - Sodium phosphate.
  § 182.6787 - Sodium pyrophosphate.
  § 182.6789 - Tetra sodium pyrophosphate.
  § 182.6810 - Sodium tripolyphosphate.

Subpart H--Stabilizers
  § 182.7255 - Chondrus extract.

Subpart I--Nutrients
  § 182.8013 - Ascorbic acid.
  § 182.8159 - Biotin.
  § 182.8217 - Calcium phosphate.
  § 182.8223 - Calcium pyrophosphate.
  § 182.8250 - Choline bitartrate.
  § 182.8252 - Choline chloride.
  § 182.8778 - Sodium phosphate.
  § 182.8890 - Tocopherols.
  § 182.8892 - [b.alpha]-Tocopherol acetate.
  § 182.8985 - Zinc chloride.
  § 182.8988 - Zinc gluconate.
  § 182.8991 - Zinc oxide.
  § 182.8994 - Zinc stearate.
  § 182.8997 - Zinc sulfate.