For sample digestion, and dilution, HNO3 is the preferred choice, as it
produces the least new interferences in the plasma, but it is not always
ideal, since some sample matrices e.g. silicates won’t digest with this
acid. In such cases, HF can be used, but then inert sample introduction
systems must be used and special care must be taken while handling
this hazardous acid. Dilute (2%) HNO3 is the most preferred acid for
sample dilution in
ICP-MS, as polyatomic ions are not increased and
nitric acid is readily available in a high purity form.