The detection capability of traditional quadrupole mass analyzers for some critical elements is severely compromised by the formation of polyatomic spectral interferences generated by either argon, solvent, or sample-based ionic species. Although there are ways to minimize these interferences — including correction equations, cool plasma technology, and matrix separation — they cannot be completely eliminated. However, a new approach called collision/reaction cell technology has recently been developed that virtually stops the formation of many of these harmful species before they enter the mass analyzer. Part IX of this series takes a detailed look at this innovative new technique and the exciting potential it has to offer.
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